Evalon Cream 15 gm is intended for topical use only and should be inserted into your vagina, using the applicator provided, directions for which are provided on the label. usually once a day, before going to bed, for the first week, then once or twice a week or once every two weeks, as instructed. Evalon Cream should be administered intra vaginally by means of a calibrated applicator (supplied) before retiring at night.