Take Temonat exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Buy Temonat 20 mg is given in a 28-day treatment cycle, and you may only need to take the medicine during the first few days of each cycle. If you are also receiving radiation treatment, you may need to take temozolomide for 6 to 7 weeks in a row during your first treatment cycle.